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Figure 2
Workflow of the simulations performed to evaluate the capacity of Tikhonov–Phillips regularization to return the original hydrodynamic radius distribution. Grey and blue boxes represent the data-generation and data-fitting steps, respectively. Figures on the right from top to bottom: (a) normal distribution, (b) light scattered by a particle at different angles according to the Mie theory, (c) simulated autocorrelation curves, (d) equation of the regularization approach required to solve a nonlinear inverse problem and (e) histograms of the fitted intensity distributions.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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