Figure 5
DLS measurements and AlphaFold model predictions of in-house samples. The 30 acquisitions were fitted separately and the estimated intensity values were then averaged. Hydrodynamic radius (Rh) distribution (blue lines) of the β-propeller domain (a), coiled-coil polypeptide (b) and IDP (c). Red dashed lines represent the expected Rh based on the molecular weight and a globular model. AlphaFold models are coloured by pIDDT values (very low, red; low, yellow; OK, green; confident, light blue; very high, violet). |