Figure 7
Output from the `slice' step of Slice'N'Dice for a predicted model from AlphaFold2 (UniProt A0A487D782) for the sequence of PDB entry 7qlr. To illustrate the better agreement between the crystal structure and the split model, the unmodified predicted model and a three-way split of the predicted model using the slice function have been structurally aligned with chain A of PDB entry 7qlr using Gesamt. (a) shows the alignment between the unmodified prediction (blue) and PDB entry 7qlr (grey). (b) shows the alignment after the model has been split three ways (light green, magenta and yellow) using the clustering algorithm employed in Slice'N'Dice. MR search models created from these three models could then be used to determine the solution. |