A user-friendly plug-and-play cyclic olefin copolymer-based microfluidic chip for room-temperature, fixed-target serial crystallography

Liu, Z.; Gu, K.K.; Shelby, M.L.; Gilbile, D.; Lyubimov, A.Y.; Russi, S.; Cohen, A.E.; Narayanasamy, S.R.; Botha, S.; Kupitz, C.; Sierra, R.G.; Poitevin, F.; Gilardi, A.; Lisova, S.; Coleman, M.A.; Frank, M.; Kuhl, T.L.

doi:10.1107/S2059798323007027

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 8
Chip after 63% (top) and 100% (bottom) transmission. The 50 µm shot spacing is clearly visible in both cases, but no change in hit rate or dehydration was found at 63% transmission. At 100% transmission dehydration and diffraction from salt crystals were found, demonstrating that the X-ray shots likely led to cracks in the COC film or pinhole defects.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 79| Part 10| October 2023| Pages 944-952

https://doi.org/10.1107/S2059798323007027

Open

access

Follow Acta Cryst. D

Search IUCr Journals		doi		Advanced search
Author		volume	page