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![[Figure 3]](ag5044fig3mag.jpg)
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Figure 3
ADP- and metal-binding site of DHX9. (a, b, c) Electron-density omit maps (Fo − Fc, 3.0σ) generated in the absence of ADP and Mg2+ for (a) human DHX9 chain A (green), (b) dog DHX9 (cyan) and (c) cat DHX9 (magenta). Mg2+ ions are shown as green spheres and ADP is shown in stick representation. (d) Interactions between the adenine and ribose of ADP (green stick representation) and human DHX9. Hydrogen bonds are shown as dashed lines; side chains that form hydrophobic or stacking interactions are labeled. (e) The coordination of Mg2+ (green sphere) is shown as green dashed lines. Hydrogen-bond interactions between ADP phosphate groups (stick representation), coordinated water molecules (red spheres) and DHX9 residues (stick representation) of human DHX9 are indicated as gray dashed lines. The DHX9 ribbon and side chains are colored as in Fig. 1 ![[link]](../../../../../../logos/arrows/d_arr.gif){kind=small} . |
![[Figure 3]](ag5044fig3.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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