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Figure 4
Superposition of DHX9 and MLE. The color scheme of the DHX9 domains is identical to that in Fig. 1[link]; MLE is colored gray. (a) Global superposition of DHX9 and MLE structures generated using all Cα atoms (dsRBD2 is not included for MLE). ADP (DHX9-bound) and ADP–AlF4 (MLE-bound) are shown in in green and gray stick representations, respectively; RNA (bound to MLE) is shown in a dark blue cartoon representation. (b) Cartoon representation of the global conformational differences seen between domains in the superposition of DHX9 (color) and MLE/RNA (gray/dark blue); dsRBD2 is included for MLE. Superpositions of individual substructures are shown: (c) MTAD-RecA1, (d) RecA2 and (e) L2-HA-OB-L3.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 79| Part 11| November 2023| Pages 980-991
https://doi.org/10.1107/S2059798323007611
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