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Figure 8
Comparison of interactions at the nucleotide-binding sites of DHX9 and MLE. DHX9 and MLE structures are superposed relative to the RecA1 domain and are colored as in Fig. 4[link]. Motif and residue labels are shown in blue or dark pink for DHX9 and in black for MLE. ADP in DHX9 and ADP–AlF4 in MLE are colored green and gray, respectively. (a) Interactions at the RecA1 interface. Mg2+ (large spheres), coordinated waters (small spheres) and their coordination (dashed lines) in DHX9 and MLE are colored to match the associated nucleotide. Only DHX9 residues are labeled for simplicity. (b) Interactions at the RecA2 interface are shown.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 79| Part 11| November 2023| Pages 980-991
https://doi.org/10.1107/S2059798323007611
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