Figure 5
Cartoon tube diagrams of the backbones of the monomer structures of apo A53_2 (beige) and apo A53_1 (green). A region displaying sizeable conformational differences (residues 60–79) is circled by a black dashed line. This region participates in dimer formation in the A53_2, A53_3 and A53_4 structures, which are very similar and differ significantly from that of A53_1. The missing regions in A53_1, i.e. residues 203–210, 254–274 and 314–320, are colored red and circled by red dashed lines. The two Zn2+ ions in A53_2 are shown as magenta spheres and the residues which bind them are displayed as sticks. |