view article
Figure 4
Neutron structure of the UOX:8AZA complex. (a) W1 is present as a neutral H2O molecule. A 2mFo − DFc neutron scattering length density map for 8AZA and the O atom of W1 is shown in grey at the +1.0σ level. An omit mFo − DFc neutron map indicates the presence of two deuterons (H1 and H2) as suggested by the elongated positive density (in green at the +3.0σ level) next to the O atom. (b) Representation of a portion of the active site highlighting the protonation of the Lys10–Thr57 dyad and the hydrogen-bonding network. H difference neutron density for Lys10NZ and Thr57OG1 is shown in green at the +3.0σ and +2.5σ levels, respectively. Hydrogen bonds are shown as grey dashed lines and their distances are shown in purple.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 79| Part 12| December 2023| Pages 1056-1070
https://doi.org/10.1107/S2059798323008793
Follow Acta Cryst. D
Sign up for e-alerts
E-alerts
Follow Acta Cryst. on Twitter
Twitter
Follow us on facebook
Facebook
Sign up for RSS feeds
RSS