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Figure 4
SAXS results for the N–VHH complex. The upper part of the figure shows the fit of the data within the Guinier region (sminRg < 0.65, smaxRg = 1.3), the GNOM fit, the distance distribution p(r) and the CRYSOL fit between the data and the molecular model that we have elaborated in order to fit the data. In the GNOM analysis of the merged profile the data are shown as black dots and the GNOM fit as a red line. The error difference between the data and the GNOM fit is shown at the bottom of the figure with black dots. The distance distribution p(r) corresponds to the merged data calculated with a maximum particle dimension Dmax of 14.6 nm (black dots). In the CRYSOL fit the error difference between the data and the molecular model is shown at the bottom of the figure with black dots. In the lower part of this figure we present a dimer of the N–VHH heterodimer fitted into the electron density calculated from the experimental data with DAMMIN. The correlation coefficient (CC) for this fit between the molecular model and the electron density is 0.85.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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