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Figure 8
Pressure induces structural change in UOX crystals. A phase transition from I222 to P21212 occurs at 600 bar, during which the tetramer switches from an α4 to an (αβ)2 assembly (shown in green and in green/cyan, respectively). A second AZA inhibitor is observed above 1500 bar (PDB entry 6ia9).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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