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Figure 7
Diffusion-based time-resolved experiments. (a) Strategies enabling the initiation of a reaction by the diffusion of a substrate or a cofactor. (b) Overview of studies conducted on emblematic targets: fluoroacetate dehalogenase (depicted using PDB entry 5k3a; Mehrabi, Schulz, Dsouza et al., 2019BB79), β-lactamase (depicted using PDB entry 7bh5; Butryn et al., 2021BB26) and xylose isomerase (depicted using PDB entry 8aw8; Mehrabi et al., 2023BB80). Colour code: protein secondary structure, white; substrate, orange; ions, green (chloride ion), red [magnesium(II) ion] and lilac [manganese(II) ion].

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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