Figure 3
The active-site-bound fragments (a) cpd-2, (b) cpd-7, (c) cpd-14, (d) cpd-16, (e) cpd-18, (f) cpd-27, (g) cpd-28 and (h) cpd-29. Hydrogen bonds are shown as black dashed lines. Halogen bonds are shown as orange dashed lines in (h). The colour code for the stick representations of the fragments is the same as described in Fig. 2, with C atoms in cyan. |