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![[Figure 2]](ih5004fig2mag.jpg)
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Figure 2
Cryo-EM structures of complex I assembly intermediates. (a) The smaller assembly intermediate of the PP module of complex I from Y. lipolytica, referred to as the early PP module intermediate, is composed of the subunits ND2 and NDUFC2, the assembly factors CIA84 and NDUFAF1, and the acyltransferase tafazzin. (b) The second intermediate (the late PP module intermediate) contains all of the subunits of the PP module of complex I. CIA84 and NDUFAF1 retain their structure and binding sites, but tafazzin is no longer bound. (c, d) Location of the modules in Y. lipolytica complex I with subunits of the early (c) and late (d) PP module intermediate coloured. The lipid bilayer was created with BioRender. |
![[Figure 2]](ih5004fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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