Figure 5
The role of CIA84 and tafazzin in the early PP module assembly intermediate. (a) Cryo-EM density of the early PP module assembly intermediate of Y. lipolytica (coloured by subunit as in Fig. 2a) with a fitted AlphaFold prediction of CIA84 (purple ribbon). (b) The structure of tafazzin. Conserved active-site residues and lipids found in the cryo-EM structure are indicated. The membrane surface is indicated in grey. |