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![[Figure 4]](jb5061fig4mag.jpg)
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Figure 4
Zoom in around the active sites of MKbur in orange and MKvar in green, where (a) and (b) are centred around the mevalonate shown in cyan lines and (c) and (d) are centred around the ATP shown in lines and the magnesium ion (Mg2+) represented as a cyan sphere (the localization of ATP is estimated by alignment with MKrat crystallized with ATP in the active site; Fu et al., 2002  ). Conserved amino acids are shown as sticks, with motifs I, II and III in pink, blue and grey, respectively. The loops involved in binding the nucleotide moiety are indicated in dark red and the lid is shown in yellow in (c) and (d). Distances in Å between elements are represented by yellow dotted lines. |
![[Figure 4]](jb5061fig4.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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