Figure 1
Crystal structure of L. monocytogenes Δ100CdaA. (a) Biochemical reaction of DAC. (b) Overall structure of the truncated monomeric Δ100CdaA. The c-di-AMP molecule, depicted in ball-and-stick mode, marks the active site. Color coding is according to conservation score: green, low; white, medium; purple, high. (c) Cartoon representation of the catalytically active Δ100CdaA dimer in its postcatalytic state with c-di-AMP bound in the active site (PDB entry 6hvl). |