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![[Figure 2]](ag5049fig2mag.jpg)
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Figure 2
Detailed views of the binding sites of the eight identified fragments. Protein residues within 4 Å are depicted as sticks; hydrogen bonds are marked as yellow dashed lines. The polder omit map (mFo − DFc) is shown at either the 3.3σ or the 3.9σ level. (a) D07, (b) B04, (c) C08, (d) B06, (e) C11, (f) E05, (g) E01, (h) H04. For fragments bound in the active sites (a) and (b), an ATP molecule is shown for reference (depicted as a green stick model, PDB entry 8c4o). |
![[Figure 2]](ag5049fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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