Figure 4
The eight fragment molecules (identified binding events) mapped on the surface of the CdaA monomer and colored according to the surface-conservation score. The individual views (90° increments) represent different views of the CdaA monomer. Two fragment molecules (B04 and D07) were localized in the highly conserved region (active site, marked with the AMP molecule colored yellow), while the remaining six fragments (B06, C08, C11, E01, E05 and H04) were identified in the nonconserved regions. |