Figure 8
Classification of the S. cerevisiae 80S ribosomal translation cycle using MRA. The box plot represents occupancies for each class across three replicates. The red line indicates the sample median, while the bottom and top of each box are the 25th and 75th percentiles of the sample, respectively. Whiskers show the farthest observations beyond the 25th and 75th percentiles. Corresponding density maps for each state after the consensus class assignment are shown with a slice through the tRNA channel. For the `P, E(partial), eEF1-tRNA' state, heterogeneous occupancy of the E-site produces a larger variance across replicates. |