Figure 14
Examples of the three conformational Trp clusters in the +4 class. (a) m0 (PDB entry 7mzy; only the Cβ atoms of non-Trp residues are shown for clarity, (b) m105 (PDB entry 4gxw), (c) p-90 (PDB entry 3s92). Note that all motifs contain hydrogen bonds from the TrpCδ1—H and amide groups to the i − 4 carbonyl, capping it with a three-centred bond. |