view article
Figure 3
Crystal packing of the IRAK4 SER crystal form. The two chains of construct IRAK4_6 in the asymmetric unit of PDB entry 8br6 are shown in green ribbon representation. The position of the triple SER mutation K400A/E401A/E402A is highlighted in magenta. Two crystal neighbours in the vicinity of these SER mutations are depicted in cyan and dark blue. The N-terminal extension (residues 165–184), which is present only in the long constructs in Table 4[link], is shown in yellow. The co-crystallized inhibitor is shown in stick representation with C atoms in orange.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 80| Part 9| September 2024| Pages 661-674
https://doi.org/10.1107/S2059798324007939
Follow Acta Cryst. D
Sign up for e-alerts
E-alerts
Follow Acta Cryst. on Twitter
Twitter
Follow us on facebook
Facebook
Sign up for RSS feeds
RSS