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Figure 11
Prenylation. Top: prenylation of cysteine involves the addition of a farnesyl group (or geranylgeranyl group; Supplementary Fig. S9) donated by farnesyl diphosphate (or geranylgeranyl diphosphate) to the side-chain thiol group. Bottom: farnesylcysteine (PDB entry 6k1z; Ji et al., 2019BB78; CCD code FAR). Positive omit density is shown in green at 3σ for the modified residue. The rest of the protein chain is represented by an orange ribbon model.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 80| Part 9| September 2024| Pages 647-660
https://doi.org/10.1107/S2059798324007794
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