Figure 8
O-Glycosylation. Top: O-glycosylation of serine or threonine involves the addition of an O-glycan to the side-chain hydroxyl group via oligosaccharide transferase (OST). Middle: O-linked glycosylation (PDB entry 2ciw; Kühnel et al., 2006 ). Omit density is shown in green at 3σ for the modified residue. The rest of the protein chain is represented by an orange ribbon model. Bottom: the symbol nomenclature for glycans (SNFG) representation is shown and was generated using the Privateer Web App (Dialpuri, Bagdonas, Schofield, Pham, Holland, Bond et al., 2024 ). |