Figure 8
O-Glycosylation. Top: O-glycosylation of serine or threonine involves the addition of an O-glycan to the side-chain hydroxyl group via oligosaccharide transferase (OST). Middle: O-linked glycosylation (PDB entry 2ciw; Kühnel et al., 2006). Omit density is shown in green at 3σ for the modified residue. The rest of the protein chain is represented by an orange ribbon model. Bottom: the symbol nomenclature for glycans (SNFG) representation is shown and was generated using the Privateer Web App (Dialpuri, Bagdonas, Schofield, Pham, Holland, Bond et al., 2024). |