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![[Figure 2]](gri5002fig2mag.jpg)
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Figure 2
(a) AlphaFold and RoseTTAFold models of ΔP1 processed by the `process predicted model' tool in CCP4i2 and used as search models for Phaser molecular replacement. The processed AlphaFold model was generated using ColabFold (version 1.5.2) and is colored red, while the processed RoseTTAFold model was generated using the Robetta server and is colored blue (Baek et al., 2021  ; Mirdita et al., 2022). (b) Superimposition of the unprocessed AlphaFold ΔP1 model (cyan) and the Δ1244 structure (orange; PDB entry 6bbk) with the ΔP1 structure (white). The region with the highest r.m.s.d. between the models is highlighted in (c); the differing side chain of residue 92 is shown and demonstrates the incorrect prediction of the positioning of Lys92 by AlphaFold. All images were generated using PyMOL version 2.5.0 (Schrödinger). |
![[Figure 2]](gri5002fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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