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Figure 4
Subtomogram averaging of apoferritin. (a) Fit of human apoferritin coordinates (PDB entry 6zsu) in the Coulomb potential map derived from particles predicted by tomoCPT. (b) Fourier shell correlation (FSC) curves comparing the resolution of maps derived from using tomoCPT (green) and template matching (pink). (c) Isosurface renderings of the Coulomb potential maps coloured by local resolution using tomoCPT (left) and template matching (right). |