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![[Figure 6]](jv5017fig6mag.jpg)
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Figure 6
Comparison of the crystal structures of PvAIII and PvAIII(K)-1. (a) Dimer AB from the PvAIII structure with important structural elements marked, i.e. the stabilization loop (SL, light violet), active site (yellow) and region corresponding to the activation loop (AL, orange). (b) Detailed view of the PvAIII active site (Thr triplet marked by red circles; residues involved in catalytic switch marked by blue circles; residues involved in substrate stabilization marked by green circles; sequence differences are indicated in red). (c) Octahedral coordination of sodium ion in the SL loop of PvAIII chain A. (d) Region corresponding in PvAIII to the AL loop, chain B, with coordinated sodium ion. (e) Crystal structure of PvAIII(K) (PDB entry 4pu6) with important structural elements marked as in (a). (f) Active site of PvAIII(K) with Thr triplet and selected side chains marked as in (b). (g) Octahedral coordination of potassium cation in the SL loop of PvAIII(K). (h) Coordination of potassium cation in the AL loop of PvAIII(K). |
![[Figure 6]](jv5017fig6.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
