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Figure 14
The expected lactone in the ligand does not bind to FABP4, but the open hydroxy acid does, contacting Arg127 and Tyr128 (not shown). Two alternate conformations of the ligand are supported by electron density.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 81| Part 8| August 2025| Pages 451-464
https://doi.org/10.1107/S2059798325006096
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