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Figure 16
N–N methyl shift in a pyrimidinone. The methyl group, as expected, would clash with the guanidinium group of Arg127 (marked in red). The pyrimidinone cannot be rotated by 180°, as this would swap the positions of the exocyclic S and O atoms. The position of the S atom (yellow), however, is clear from the electron density. |

journal menu![[Figure 16]](gm5113fig16.jpg)
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