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![[Figure 2]](gm5113fig2mag.jpg)
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Figure 2
A relative 180° rotation of the benzisoxazole ring is observed in 7fwx (FABP4, dark blue) and 7fvz (FABP4_5, cyan). Position 34 is an alanine in FABP4 but is a glycine in FABP5. The presence of the alanine methyl side chain is incompatible with a methyl group on the heterocycle of the ligand, leading to a flip of the entire group. |
![[Figure 2]](gm5113fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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