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![[Figure 4]](gm5113fig4mag.jpg)
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Figure 4
Electron density-based assignment of the correct diastereomer. The bond in question is marked in red. (a) Instead of (2R,3R), this 2-(phenoxymethyl)-1-phenyl-pyrrolidine-3-carboxylic acid is (2R,3S). (b) Instead of (1S,2S,5R), this 3-[2-(3-thienyl)acetyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid is (1S,2R,5R). (c) Only a single one of the six stereocenters in this compound was found to be wrong. Instead of (1S,2R,6R,7S,8R,9R), the 5-(4-chlorophenyl)-9-methyl-3-oxa-4-azatricyclo[5.2.1.02,6]dec-4-ene-8-carboxylic acid is (1S,2R,6R,7S,8R,9S). Unfortunately, no NMR or MS analysis was performed for any of these three compounds. |
![[Figure 4]](gm5113fig4.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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