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Figure 4
Five examples where SAD phasing based on bromine-containing ligands was successful. The SAD maps in gray are contoured with a radius of 10 Å at 1 r.m.s.d. around the ligand. SAD maps in magenta are contoured at 5 r.m.s.d. For the ligand in 7g0b, the Br atom did not display a signal beyond 5 r.m.s.d. For the structures 7fww and 7g09, a signal of >5 r.m.s.d. is displayed by the S atoms in the ligands. The final protein models are superimposed on the SAD maps. All structures are hFABP4 in space group 19, except 7g0b, which is hFABP5 in space group 96.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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