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![[Figure 1]](chr5008fig1mag.jpg)
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Figure 1
Overview of Nsp1NTD and binding fragments identified in previous studies. Nsp1NTD is shown as a grey cartoon and surface. N and C indicate the N- and C-terminus. (a) Overview of functionally important sites in Nsp1NTD. Functionally important residues are shown as sticks, and functionally important areas are colour-coded, with purple showing the ribosomal binding site, yellow the RNA-binding site and teal the binding site for DNA polymerase α. (b) Surface view of Nsp1NTD, with the hydrophobic pocket highlighted in red. (c) Fragments identified in previous studies. Fragments are shown as sticks and colour-coded based on the study that they have been identified in. Orange: Ma et al. (2022  ), PDB entries 8ays, 8az8, 8crf, 8crk and 8crm. Red: Ma et al. (2024), PDB entries 8rf2, 8rf3, 8rf4, 8rf5, 8rf6, 8rf8, 8rfc, 8rfd and 8rff. Light blue: Borsatto et al. (2022), PDB entry 8a4y. |
![[Figure 1]](chr5008fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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