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![[Figure 6]](chr5008fig6mag.jpg)
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Figure 6
Binding modes of F2X-Entry fragments binding to Nsp1NTD. Nsp1NTD is shown as a cartoon in grey, with residues that make up the binding pocket or interact with the fragment shown as sticks. Fragments are shown in blue, water molecules are shown as red spheres and hydrogen bonds as dashed lines in black. A 2D diagram of each fragment is shown as an inset. The name of the respective fragment is shown at the bottom right corner. (a) Apo structure of Nsp1NTD showing waters in the binding pocket where most of the fragments bind. (b)–(l) Binding mode of fragments C02, C06, D10, E01, E04, E12, F02, F09, B03 site 1, B03 site 2 and B08, respectively. For B03 site 2, a crystal symmetry-related molecule of Nsp1NTD that contacts the fragment is shown in teal. |
![[Figure 6]](chr5008fig6.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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