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Figure 7
Overview of functionally important regions and fragment hits mapped onto Nsp1NTD. Fragments are shown as green and blue sticks. Nsp1NTD is shown in grey, and functionally important sites are colour-coded, with yellow showing the proposed RNA-binding site, purple showing the ribosomal binding site and teal showing the DNA polymerase α-binding site. Residues that are important for individual interactions are shown as sticks, and residues that have been experimentally shown to be important for several of the functions of Nsp1 are shown in red. |
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