Cryo-EM single-particle analysis expanding towards increasingly native samples

Moecking, J.; Zeev-Ben-Mordehai, T.

doi:10.1107/S2059798325008332

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

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Figure 1
Cryo-EM single-particle analysis (SPA) and cryo-ET subtomogram averaging (STA) classically have defined sample preparation, data collection and processing (upper panel). Recent studies demonstrate that the boundaries between the techniques are blurring (lower panel). (Multiple illustrations from NIAID NIH BIOART Source (https://bioart.niaid.nih.gov).

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 81| Part 11| November 2025| Pages 587-597

https://doi.org/10.1107/S2059798325008332

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