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![[Figure 8]](chr5007fig8mag.jpg)
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Figure 8
Molecular binding modes of three different PLK1 inhibitor classes. Comparison of three co-crystal structures with PLK1K225D/K226A in (a) with compound 1 (C atoms in yellow), in (b) with BI 2536 (C atoms in orange) and in (c) with GSK461364 (C atoms in green). Classical hydrogen bonds are shown as yellow dotted lines; nonclassical (C—H⋯O=C) hydrogen bonds are depicted as grey dotted lines. |
![[Figure 8]](chr5007fig8.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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