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Figure 1
Macroscopic crystals of the Gab1–SHP2 complex demonstrate disorder. (a) Light microscope view of needle-like Gab1–SHP2 crystals grown in a hanging drop using the vapor-diffusion method. (b) After 18 days, small plate-like crystals grew in the same drop. (c, d) X-ray diffraction patterns of two independent plate-like crystals (b) reveal Bragg reflections up to around 2.7 Å resolution (white arrows), but exhibit multiple lattices and high mosaicity.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 82| Part 1| January 2026| Pages 11-22
https://doi.org/10.1107/S2059798325011258
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