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![[Figure 4]](ag5062fig4mag.jpg)
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Figure 4
Molecular interactions between SmCD1 and Nb10C9. (a) Molecular interactions between the backbone of SmCD1 (light yellow) and Nb10C9 (turquoise), with the backbone of the propeptide sequence coloured orange. PDBePISA-identified interacting groups are shown in stick notation. Salt bridges are indicated by red dashed lines and hydrogen bonds by blue dashed lines. (b) LigPlot+ schematic (Laskowski & Swindells, 2011  ) of Nb10C9 (upper subpanel) and SmCD1 (lower subpanel) residues participating in the CDR interface. Identified interactions are represented by dashed lines, whilst residues present at the interface are represented as surfaces. (c) Binding of SmCD1 to Nb10C9 via the FR interface. Molecular interactions between the backbone of SmCD1 (light yellow) and Nb10C9 (turquoise) are shown. Residues involved in the FR interface are coloured teal. PDBePISA-identified interacting groups are shown in stick notation. Salt bridges are indicated by red dashed lines and hydrogen bonds by blue dashed lines. Bond distances are represented in Å. (d) Titration ELISA of Nb10C9 mutants, Nb10C9_KO1 and Nb10C9_KO2, bound to 50 nM SmCD1. |
![[Figure 4]](ag5062fig4.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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