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Figure 3
Structural response of hhMb to X-ray-induced reduction. (a) Fobs(n)Fobs(1) Fourier difference maps corresponding to dose points 86.4 and 446.4 kGy at CT contoured at a ±3.5σ level (orange, negative; blue, positive) and superimposed on the refined 14.4 kGy model (PDB entry 9t6y). (b) Integrated negative difference electron density at the location of the haem iron as a function of dose, building up with a dose constant of 79.5 kGy. (c) Fobs(n)Fobs(1) Fourier difference maps corresponding to dose points 65.0, 130.0 and 260.0 kGy at RT contoured at a ±3.5σ level (orange, negative; blue, positive) and superimposed on the refined 32.5 kGy model (PDB entry 9t6v).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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