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Figure 4
The substrate-binding cavities in TANGO2 and four cysteine Ntn-hydrolases. The overall view of the cavity substructures near the N-terminal cysteines of TANGO2 (a) and four cysteine Ntn-hydrolases structures (b–e). The cavity surface was colored by molecular lipophilic potential (MLP), ranging from dark cyan (most hydrophilic) to white (neutral) to dark goldenrod (most lipophilic). N-terminal cysteines are highlighted in red. The characterizations of each cavity are summarized in Table 2[link].

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 82| Part 4| April 2026| Pages 383-396
https://doi.org/10.1107/S2059798326001968
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