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Figure 3
RADDOSE-3D results. (a) Average DDWDs (navy) and FWDs (lavender) estimated for all the wedge (dashed) and pseudohelix (solid) datasets. It is evident that the pseudohelix datasets progressively accumulate dose. The diffraction decay weighting is evident from the slower DDWD accumulation. (b) Distribution of dose in the crystal after the collection of 38 wedge datasets. Each collection segment contains a very high-dose region centered around the rotation axis, which exceeds the Garman limit of 30 MGy. The wedges were spaced apart far enough to prevent significant accumulation of dose in neighboring wedges. Dose isosurfaces are drawn at 5 MGy (light blue), 10 MGy (blue) and 30 MGy (red). All graphs were created using the ggplot2 package (v4.0.3) and (b) was made using ParaView (v6.0.1; Wickham et al., 2026View full citation; Ayachit, 2015View full citation).

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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