Perspectives for pharmaceutical screening at XFEL sources using the example of Lassa virus endonuclease

Falke, S.; Reinke, P.Y.A.; Rosenberg, D.; Fischer, P.; Meyer, J.; Galchenkova, M.; Tolstikova, A.; Mariani, V.; Senst, J.M.; Lewe, P.; Witt, S.; Wagner, A.; Chapman, H.N.; Hunter, M.; Günther, S.; Meents, A.

doi:10.1107/S2059798326009435

Figure 4
Comparison of active sites and ligand poses. 2mF_o − DF_c density maps of (a) the apo protein structures, (b) the DPBA complexes and (c) the BXA complexes. Maps are shown as blue mesh at a 1σ contour level.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 82| Part 10| October 2026| Pages 1181-1194

https://doi.org/10.1107/S2059798326009435

Open

access