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Figure 2
Overview of ligand classes and structural features in co-crystallized structures of GSK3β. (a) Frequency of ligand classes in GSK3β structures deposited in the PDB. (b) Scatter plot showing the crystallographic resolution (Å) distribution by select co-crystallized ligand classes for 108 GSK3β structures: ATP-like ligand (n = 4), Type I ligand (n = 88) and peptide (n = 16). Apo structures (no ligand, n = 2) and structures with Type I1/2 ligand (n = 1) were excluded from this panel. (c) Grouped bar plot highlighting the distribution of ligand classes across different GSK3β dihedral labels.

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BIOLOGY
ISSN: 2059-7983