Beyond monofunctionality: structural perspectives on phenol oxidase side activity in a catalase

Ferousi, C.; Kosinas, C.; Pantelakis, O.I.; Nikolaivits, E.; Topakas, E.; Dimarogona, M.

doi:10.1107/S2059798326009848

Figure 5
Overall view of the ClCPO tetramer highlighting the channels that connect the haem active site to the solvent environment. (a) Detailed view of the channels shown as a mesh with different colours. (b) Top view of the main and secondary channels shown as a mesh. The experimentally observed Ser and CAQ positions are located at the junction of the two channels. (c) CAQ bound at the juncture of the main with the secondary channel shown in stick representation. Hydrogen bonds of the CAQ moiety to surrounding residues are shown as yellow dashed lines. (d) CAQ view in stick representation modelled within a 2F_o − F_c map shown as a blue mesh.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 82| Part 11| November 2026|

https://doi.org/10.1107/S2059798326009848

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