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Figure 1
Simulation of 3dcon processing with a phantom of isolated particles. A tomographic reconstruction suffers characteristic artifacts related to missing wedges, large and small. These are seen most strikingly in a cross-section perpendicular to the tilt axis. Deconvolution with a point spread function (PSF, shown in denominator) representing the tilt geometry effectively suppresses these artifacts.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
Volume 82| Part 11| November 2026| Pages 1240-1250
https://doi.org/10.1107/S205979832600999X