most read articles
These are the most read articles in the last six months.
Protein structure prediction by AlphaFold2: are attention and symmetries all you need?. (2021). Acta Cryst. D77, 982-991.
Molecular-dynamics simulation methods for macromolecular crystallography. (2023). Acta Cryst. D79, 50-65.
20 years of crystal hits: progress and promise in ultrahigh-throughput crystallization screening. (2023). Acta Cryst. D79, 198-205.
Protein model refinement for cryo-EM maps using AlphaFold2 and the DAQ score. (2023). Acta Cryst. D79, 10-21.
Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules. (2022). Acta Cryst. D78, 1337-1346.
Accelerating crystal structure determination with iterative AlphaFold prediction. (2023). Acta Cryst. D79, 234-244.
Putting AlphaFold models to work with phenix.process_predicted_model and ISOLDE. (2022). Acta Cryst. D78, 1303-1314.
Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy. (2023). Acta Cryst. D79, 111-121.
Implications of AlphaFold2 for crystallographic phasing by molecular replacement. (2022). Acta Cryst. D78, 1-13.
Cryo-EM single-particle structure refinement and map calculation using Servalcat. (2021). Acta Cryst. D77, 1282-1291.
Using deep-learning predictions of inter-residue distances for model validation. (2022). Acta Cryst. D78, 1412-1427.
Cryo-EM structure of adeno-associated virus 4 at 2.2 Å resolution. (2023). Acta Cryst. D79, 140-153.
2023 update of template tables for reporting biomolecular structural modelling of small-angle scattering data. (2023). Acta Cryst. D79, 122-132.
Best practices for time-resolved serial synchrotron crystallography. (2022). Acta Cryst. D78, 14-29.
Structural and functional characterization of a multi-domain GH92 α-1,2-mannosidase from Neobacillus novalis. (2023). Acta Cryst. D79, 387-400.
Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. (2023). Acta Cryst. D79, 304-317.
Metalloprotein catalysis: structural and mechanistic insights into oxidoreductases from neutron protein crystallography. (2021). Acta Cryst. D77, 1251-1269.
Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed. (2022). Acta Cryst. D78, 599-612.
Correction of rhodopsin serial crystallography diffraction intensities for a lattice-translocation defect. (2023). Acta Cryst. D79, 224-233.
FLEXR: automated multi-conformer model building using electron-density map sampling. (2023). Acta Cryst. D79, 354-367.
Microsecond melting and revitrification of cryo samples: protein structure and beam-induced motion. (2022). Acta Cryst. D78, 883-889.
How do I get the most out of my protein sequence using bioinformatics tools?. (2021). Acta Cryst. D77, 1116-1126.
Crystal structure of a polyglycine hydrolase determined using a RoseTTAFold model. (2023). Acta Cryst. D79, 168-176.
The LH–DH module of bacterial replicative helicases is the common binding site for DciA and other helicase loaders. (2023). Acta Cryst. D79, 177-187.
Towards the standardized presentation and publication of small-angle scattering data from biomolecules in solution. (2023). Acta Cryst. D79, 98-99.
Time-resolved serial femtosecond crystallography on fatty-acid photodecarboxylase: lessons learned. (2022). Acta Cryst. D78, 1131-1142.
Likelihood-based signal and noise analysis for docking of models into cryo-EM maps. (2023). Acta Cryst. D79, 271-280.
On bias, variance, overfitting, gold standard and consensus in single-particle analysis by cryo-electron microscopy. (2022). Acta Cryst. D78, 410-423.
Determining the oxidation state of elements by X-ray crystallography. (2022). Acta Cryst. D78, 238-247.
CCP4 Cloud for structure determination and project management in macromolecular crystallography. (2022). Acta Cryst. D78, 1079-1089.
A GH115 α-glucuronidase structure reveals dimerization-mediated substrate binding and a proton wire potentially important for catalysis. (2022). Acta Cryst. D78, 658-668.
Lipidic cubic phase serial femtosecond crystallography structure of a photosynthetic reaction centre. (2022). Acta Cryst. D78, 698-708.
Using photocaging for fast time-resolved structural biology studies. (2021). Acta Cryst. D77, 1218-1232.
Introduction to the virtual thematic issue on room-temperature biological crystallography. (2023). Acta Cryst. D79, 268-270.
Protein dynamics developments for the large scale and cryoEM: case study of ProDy 2.0. (2022). Acta Cryst. D78, 399-409.
Fast fragment- and compound-screening pipeline at the Swiss Light Source. (2022). Acta Cryst. D78, 328-336.
High-resolution structure determination using high-throughput electron cryo-tomography. (2022). Acta Cryst. D78, 817-824.
Exiting the tunnel of uncertainty: crystal soak to validated hit. (2022). Acta Cryst. D78, 1294-1302.
MrParse: finding homologues in the PDB and the EBI AlphaFold database for molecular replacement and more. (2022). Acta Cryst. D78, 553-559.
A tetramerization domain in prokaryotic and eukaryotic transcription regulators homologous to p53. (2023). Acta Cryst. D79, 259-267.
A case for glycerol as an acceptable additive for single-particle cryoEM samples. (2022). Acta Cryst. D78, 124-135.
Elucidation of protein function using computational docking and hotspot analysis by ClusPro and FTMap. (2022). Acta Cryst. D78, 690-697.
Structural basis of human LRG1 recognition by Magacizumab, a humanized monoclonal antibody with therapeutic potential. (2022). Acta Cryst. D78, 725-734.
Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography. (2022). Acta Cryst. D78, 964-974.
Theoretical 3D electron diffraction electrostatic potential maps of proteins modeled with a multipolar pseudoatom data bank. (2022). Acta Cryst. D78, 1010-1020.
Structural insight into an anti-BRIL Fab as a G-protein-coupled receptor crystallization chaperone. (2023). Acta Cryst. D79, 435-441.
The crystal structure of CbpD clarifies substrate-specificity motifs in chitin-active lytic polysaccharide monooxygenases. (2022). Acta Cryst. D78, 1064-1078.
Development of CryoVR, a virtual reality training system for hands-on cryoEM operations. (2022). Acta Cryst. D78, 903-910.
Right-handed Z-DNA at ultrahigh resolution: a tale of two hands and the power of the crystallographic method. (2023). Acta Cryst. D79, 133-139.
Sequence-assignment validation in cryo-EM models with checkMySequence. (2022). Acta Cryst. D78, 806-816.
Structural and functional investigation of the human snRNP assembly factor AAR2 in complex with the RNase H-like domain of PRPF8. (2022). Acta Cryst. D78, 1373-1383.
Global fitting of multiple data frames from SEC–SAXS to investigate the structure of next-generation nanodiscs. (2022). Acta Cryst. D78, 483-493.
Verification: model-free phasing with enhanced predicted models in ARCIMBOLDO_SHREDDER. (2022). Acta Cryst. D78, 1283-1293.
Multivariate estimation of substructure amplitudes for a single-wavelength anomalous diffraction experiment. (2023). Acta Cryst. D79, 339-344.
ModelCraft: an advanced automated model-building pipeline using Buccaneer. (2022). Acta Cryst. D78, 1090-1098.
Structural basis for substrate recognition in the Phytolacca americana glycosyltransferase PaGT3. (2022). Acta Cryst. D78, 379-389.
Crystal structure of the putative cell-wall lipoglycan biosynthesis protein LmcA from Mycobacterium smegmatis. (2022). Acta Cryst. D78, 494-508.
Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis. (2023). Acta Cryst. D79, https://doi.org/10.1107/S2059798323003613.
Crystallographic and X-ray scattering study of RdfS, a recombination directionality factor from an integrative and conjugative element. (2022). Acta Cryst. D78, 1210-1220.
A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs. (2022). Acta Cryst. D78, 268-277.
Knowledge-based prediction of DNA hydration using hydrated dinucleotides as building blocks. (2022). Acta Cryst. D78, 1032-1045.
Highlighting the factors governing transglycosylation in the GH5_5 endo-1,4-β-glucanase RBcel1. (2022). Acta Cryst. D78, 278-289.
Pivotal role of a conserved histidine in Escherichia coli ribonuclease HI as proposed by X-ray crystallography. (2022). Acta Cryst. D78, 390-398.
Structural snapshot of a glycoside hydrolase family 8 endo-β-1,4-glucanase capturing the state after cleavage of the scissile bond. (2022). Acta Cryst. D78, 228-237.
Detecting ice artefacts in processed macromolecular diffraction data with machine learning. (2022). Acta Cryst. D78, 187-195.
Dependence of crystallographic atomic displacement parameters on temperature (25–150 K) for complexes of horse liver alcohol dehydrogenase. (2022). Acta Cryst. D78, 1221-1234.