forthcoming articles
The following articles are a selection of those recently accepted for publication in IUCrJ.
See also Forthcoming articles in all IUCr journals.
research papers
Linking solid-state phenomena via energy differences in `archetype crystal structures'
Solid-state phenomena like disorder, polymorphism but also the occurrence of high-Z′ crystal structures can be linked via energy differences in `archetype crystal structures', which will permit better prediction of their occurrence.
topical review
RCSB Protein Data Bank: supporting research and education worldwide through explorations of experimentally determined and computationally predicted atomic level 3D biostructures
The RCSB PDB research-focused web portal at https://www.rcsb.org/ provides important tools and resources to search, visualize and analyze experimentally determined 3D biostructures alongside computed structure models of proteins predicted using artificial intelligence/machine-learning based tools.
research papers
Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity
The human peptidylarginine deiminase type VI (PAD6) is essential in oocyte and embryonic development, as a component of the supramolecular assemblies called cytoplasmic lattices. The crystal structure presented here suggests PAD6 assembles as a dimer resembling other PADs, albeit with compromised abilities to bind Ca2+ and substrates. This aligns with existing in vitro data which indicate an enzymatically inactive isoform of PAD.
research papers
Nanostructure and dynamics of N-truncated copper amyloid-β peptides from advanced X-ray absorption fine structure
An X-ray absorption spectroscopy electrochemical cell was used to collect high-quality X-ray absorption spectroscopy measurements of N-truncated Cu:amyloid-β (Cu:Aβ) samples under near-physiological conditions. The geometry of binding sites for the copper binding in Aβ4–8/12/16 and the ability of these peptides to perform redox cycles in a manner that might produce toxicity in human brains were determined.