Crystallization of the catalytic domain of murine terminal deoxynucleotidyl transferase

The catalytic domain of murine terminal deoxynucleotidyl transferase (TdT) has been crystallized in the space group P2₁2₁2₁, with unit-cell parameters a = 47.1, b = 86.2, c = 111.7 Å. The crystals diffract to a resolution of 2.4 Å using synchrotron radiation and a full data set has been collected from the native crystals. The enzyme was shown to be active in the crystalline state.