2,6-Diamino-4-chloropyrimidine–succinic acid (2/1)

In the title 2:1 co-crystal, the complete succinic acid molecule is generated by a crystallographic centre of symmetry.

In the title 2:1 co-crystal, 2C 4 H 5 ClN 4 ÁC 4 H 6 O 4 the complete succinic acid molecule is generated by a crystallographic centre of symmetry. In the crystal, pairwise O-HÁ Á ÁN and N-HÁ Á ÁO hydrogen bonds link the pyrimidine and succinic acid molecules, generating R 2 2 (8) loops. The pyrimidine molecules are linked by pairwise N-HÁ Á ÁN hydrogen bonds, again generating R 2 2 (8) loops. Collectively, the hydrogen bonds link the components into corrugated (100) sheets. The Hirshfeld surface is presented.

Structure description
Some aminopyrimidine derivatives are used as antifolate drugs (Hunt et al., 1980). The crystal structures of various aminopyrimidine derivatives (Schwalbe & Williams, 1982;Edison et al., 2014;Thanigaimani et al., 2012) have been reported. In the present study, the synthesis and structure of the title 2:1 co-crystal are described.

Figure 2
Partial packing diagram of the title compound showing hydrogen bonds as dashed lines.

Figure 3
The Hirshfeld surface mapped over d norm for the title compound.

Figure 1
The molecular structure of the title compound showing 50% displacement ellipsoids and hydrogen bonds indicated by dashed lines. Symmetry code: (i) 2 À x, 3 À y, 1 À z.  Special details Geometry. All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes.